On the relationship between Type-D personality and cardiovascular healt

Abstract

Background. The combination of high negative affectivity and high social inhibition designates a personality subtype (Type D) that has been associated with disparities in cardiovascular (CV) health. We investigated the relationship between Type D personality and CV risk factors, outcomes, and biomarkers in patients with acute coronary syndrome (ACS). Methods. Ninety-nine patients completed a survey including a measure of Type D personality. Anthropometric measures and fasting blood samples were taken within three days after the cardiovascular event. Findings. Patients with larger scores in Type D personality experienced a more severe ACS (i.e., they had more obstructed vessels and needed more stent implants). Type D personality was also related to a worse lipid profile (less high-density lipoprotein [HDL] cholesterol and more triglycerides) and more inflammation (more platelets) in patients with ACS. HDL cholesterol partially mediated the relationship between Type D personality and the number of obstructed arteries. Discussion. The increase in risk in ACS patients with Type D personality could be at least partially due to preventable risk behaviors like healthy diet and exercise.