Implicit processing of symptom and illness-related information in chronic
fatigue syndrome: a systematic review
Authors
A. Hughes
C. Hirsch
T. Chalder
R. Moss-Morris
Abstract
Background: Cognitive behavioural models propose that the way in which
people with Chronic Fatigue Syndrome (CFS) process information, specifically how they attend to
and interpret illness related information, may play an important role in symptom maintenance.
This systematic review investigates whether people with CFS have implicit biases in how they
process information. Methods: Electronic databases were searched using CFS and experimental
methodology search terms. Twelve studies measured attention and interpretative bias for illness
related information in CFS. Findings: The evidence for implicit biases was dependant on the
methodology employed as well as the type and duration of the stimuli presented. There was
preliminary evidence to suggest that people with CFS have illness related top down processing
biases which affects how information is interpreted and attended to. Discussion: A clinical
implication of these findings is that such processing biases may maintain negative illness
beliefs and symptoms in people with CFS. This review highlights methodological issues in
experimental design and makes recommendations for future research to forge a consistent
approach in implicit processing research.