Background: Health psychology interventions are increasingly expected to improve subjective well-being (SWB), rather than health-related quality of life (HRQOL) only. However, little is known about how SWB relates to HRQOL and other quality of life (QOL) domains among HIV-patients. Methods: HIV-patients treated in the Netherlands completed a cross-sectional survey on SWB (Satisfaction With Life Scale); HRQOL (SF-12); social, financial, sexual, and environmental well-being (WHO-QOL), as well as demographic and clinical characteristics. Exploratory structural equation modeling was conducted in AMOS to predict SWB. Findings: The questionnaire was completed by 191 participants. In univariate analyses, all (HR)QOL domains were significantly related to SWB (range r=.17-.42). Physical health (?=.14; p<.05), mental health (?=.27; p<.01), and environmental well-being (?=.41; p<.01) directly predicted SWB, while financial and social well-being explained SWB indirectly. Discussion: Health psychology interventions among HIV-patients are mostly focused on mental and physical health. To further promote SWB, services should also focus on promoting environmental, financial, and social well-being.
