Behaviour change interventions risk of bias in trial-based and model-based economic evaluations

Abstract

Objective: Several biases can occur when performing HTA/economic evaluations of Behaviour change intervention. It is therefore important for decision makers to be able to assess these biases and for researchers to minimize them. This presentation addresses selected types of bias in trial-based and model-based economic evaluations. Methods: Narrative review discussing sources of bias in economic. Biases were identified through literature review and expert meetings and attached to the guideline chapters respectively. Articles that illustrate the different bias were also retrieved. Results: We identified several biases and assigned them to a particular trial phase. A distinction is made between pre-trial biases, biases during the trial and biases that are relevant after the actual trial. Biases are discussed in detail with their influence on the economic evaluation outcomes. Conclusion: In order to avoid bias in economic evaluations, one has to take notice of published guidelines. The development of a checklist addressing biases in economic evaluation might lead to a better understanding and quality of economic evaluation, from researchers as well as from policy-maker’s perspective.