Aims: This symposium reports on the development and evaluation of three
behaviour change interventions: the Long Live Love sexual-education intervention for
high-school students in the Netherlands ; the PREPARE HIV-prevention intervention targeting
youth in South African schools; the AIMS-intervention to promote HIV-medication adherence among
adult patients in the Netherlands. All interventions have been developed according to
Intervention Mapping principles and have been evaluated in multi-site, randomised controlled
trials. We will report the findings of these trials, including the lessons learned during
development, implementation and process & effect evaluations. Rationale: The theme of this
year’s conference is Principles of behaviour change in health and illness. All three behaviour
change interventions have been systematically developed based on Intervention Mapping
principles; they target healthy populations and people with a chronic illness; and they have
recently been evaluated in large-scale, (cluster) randomised trials to examine (cost)
effectiveness. Reporting on the intervention-development rationale, the results and lessons
learned in these three sophisticated trials corresponds perfectly with the conference theme and
would enable timely reporting of newly-available findings to EHPS delegates. Summary:
Presentation 1 introduces the principles of Intervention Mapping, before illustrating how these
have been applied in the development of a sexual education program for high-school students in
the Netherlands. The 2nd presentation will build on this and add the perspective of cultural
relevance/sensitivity in developing and implementing an HIV-prevention for high-school students
in South Africa. Presentation 3 and 4 will report on the development, implementation and
evaluation of an HIV-treatment adherence intervention for ethnically diverse HIV-patients in
the Netherlands. The outcome and process evaluations in the first 2 presentations focus on
self-reported determinants and behaviour patterns, while the last 2 presentation will aim for
changing objective clinical outcomes and establishing programme cost-effectiveness. Combined,
these presentations will showcase the state-of-the-art in intervention development and
evaluation.